About this episode

Published October 25th, 2025, 11:00 am

Each week Hot off the Wire looks at a variety of stories in business, science, health and more. This week's headlines include:

  • COVID-19 vaccines may help some cancer patients fight tumors.
  • ICE's use of full-body restraints during deportations raises concerns over inhumane treatment.
  • Most Americans are concerned about higher health care costs next year, an AP-NORC poll finds.
  • Disney+ and Hulu cancellations rose after ABC briefly pulled 'Jimmy Kimmel Live!'.
  • What Americans think about legal sports betting, according to recent polls.
  • Coast Guard audio captures stranded family's mayday call. 'Our ship burned while we were sleeping'.
  • Another US strike in Caribbean targets alleged drug-running boat, killing 6, Hegseth says.
  • US is sending an aircraft carrier to Latin America in major escalation of military buildup.
  • Trump says he's ending trade talks with Canada over TV ads.
  • Social Security recipients get a 2.8% cost-of-living boost in 2026, average of $56 per month.
  • US inflation stays elevated but prices rose less than feared last month.
  • North Carolina adopts new Trump-backed US House districts aimed at gaining a Republican seat.
  • 14 migrants dead after dinghy sinks in the Aegean off Turkey's coast.
  • EU accuses Meta and TikTok of breaching transparency rules.
  • Israeli man's sentence over illegal development in Cyprus' breakaway north sends a stark warning.
  • Japan's new leader vows to further bolster defense buildup and spending as regional tensions rise.
  • What to know about Ireland's election as the country votes for a new president.
  • Giant floating pumpkin races draw thousands to annual event in Oregon.
  • Rare dinosaur mummies help scientists recreate their prehistoric lives.
  • Chiefs cornerback Jaylen Watson opens up about his underdog story.
  • On this week's AP Religion Roundup, King Charles visits the Vatican and Venezuela receives its first Catholic saint.

—The Associated Press

About this program

Host Terry Lipshetz is managing editor of the national newsroom for Lee Enterprises. Besides producing the daily Hot off the Wire news podcast, Terry conducts periodic interviews for this Behind the Headlines program, co-hosts the Streamed & Screened movies and television program and is the former producer of Across the Sky, a podcast dedicated to weather and climate.

Theme music

The News Tonight, used under license from Soundstripe. YouTube clearance: ZR2MOTROGI4XAHRX

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Hot Off The Wire

COVID-19 vaccines may help some cancer patients fight tumors

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